Reversing Diabetes by Restoring Bowel Health

Majid Ali, M.D.

 Majid Ali, M.D.

Restoring bowel ecology is one of my top priorities for reversing diabetes. Why is it so? My simple answer: Because I cannot help my patients reverse diabetes without it. I take time to explain to them how insults to gut ecology set the stage for insulin receptor dysfunction, insulin resistance, and ultimately diabetes. In a companion article entitled “Seed, Feed, and Weed Approach to Bowel Health,” I offer my guuidelines for restoring bowel ecology.


How Did I get So Preoccupied With Gut Ecology?

In the 1970s, based on a study of more than 4,500 colon and 1,100 stomach biopsies, I introduced the term “bowel ecology” and published several papers to describe how disruptions of this ecosystem set the stage for the development of chronic diseases. The immune system, in this view, is rooted in the soil of the bowel contents. This was one of the seven insights my microscopes and patients provided. It would take me over two decades to recognize that the bowel ecosystem, more than other ecosystem in the human body, serves well the Oxygen King of human biology to prevent disease and prolong life, or mis-serves it to cause chronic diseases and premature aging. This was another of my seven insights. I devoted my book Oxygen and Aging (2000) to this core notion.

The Oxygen Model of Diabetes

It was my early work in the 1970s that eventually led to propose the Oxygen Model of Insulin Toxicity and the Oxygen Model of Diabetes. I devote separate articles, video seminars, and short videos to these subjects at this website. The flora of various compartments of the gut flora (colon flora, small intestine flora, stomach flora, and oral flora) constitute an enormous ever-changing microbial kaleidoscope which preserves health. At one level, the human body can be seen as a wide range of microbial habitats.

When disrupted, changes in such microbial communities play pivotal roles in the development of all chronic disease, increasing diabetes, both of type and type 2 variants.

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