Diabetes Simplified


Majid Ali, M.D.

Is diabetes a sugar problem?

I answer this and many related questions about diabetes in my free diabetes course described below.

Body Organs of Special Interest in Oxygen Models of Diabetes and Insulin Toxicity

  1. Gut
  2. Liver
  3. Thalamus in the Brain
  4. Muscles
  5. Pancreas

Why Is the pancreas gland that produces insulin so low in the order of body organs?

I invite readers to keep this question in the mind as they consider Dr. Ali’s Course on Diabetes Reversal.


For full explanation of my answer, please read more at Dr. Ali’s Diabetes Course by clicking at the link below.





Majid Ali, M.D.

My Free Diabetes Course Has Two Parts: (1) Part One – Dr. Ali’s Insulin Toxicity Course; and (2) Part Two: Dr. Ali’s Diabetes Reversal Course. The first part of the course concerns the problem and the second part the solution. 

Scientific Basis of Insulin-Based Diabetes Reversal

Scientific Basis of Dr. Ali’s Diabetes Insulin Toxicity and Diabetes Reversal Courses

  1. Molecular Biology of Oxygen
  2. Insulin homeostasis

Five Threats to Humankind:

  1. Developmental Challenges of the Unborn
  2. Diabetes
  3. Dialysis
  4. Dementia
  5. Disability

All  five are rooted in insulin toxicity. I anticipate that some readers will roll their eyes on the first item listed above. That only means they are not aware of the frequency with which hyperinsulinism is encountered in children with autism, dysautonomia, OCD, POTS, and related neurodevelopmental challenges faced by children in prenatal and postnatal lives.


Oxygen Models of Insulin Toxicity and Diabetes Reversal Five Threats to Humankind:

Dr. Ali’s Insulin Toxicity Course and Dr. Ali’s Diabetes Reversal Course are based on Oxygen Models of Diabetes and Insulin Toxicity. Simply stated, these models explains all aspects of Type 2 diabetes—causes, clinical course, consequences, and control—on the basis of disturbed oxygen function. A full description of these models is included at the end of this article.

Body Organs of Special Interest in Oxygen Models of Diabetes and Insulin Toxicity

  1. Gut
  2. Liver
  3. Thalamus in the Brain
  4. Muscles
  5. Pancreas

Why Is the pancreas gland that produces insulin so low in the order of body organs?

I invite readers to keep this question in the mind as they consider my Course on Diabetes?


The Gut-Diabetes Connection

 The Gut-Diabetes Connections

  • Throat
  • Esophagus
  • Stomach
  • Small intestine
  • Large intestine

Digestion starts within the mouth by the action of the enzymes in saliva. It then takes full effect within the stomach and some nutrients are also absorbed into the bloodstream here. Partially digested food known as chyme then undergoes further digestion mainly in the first part of the small intestine known as the duodenum. The small intestine, or small bowel, is the longest part of the gut and gradually the food is completely digested and almost all the nutrients are absorbed into the bloodstream.

The Thalamus-Feeding-Weight-Diabetes Connections


The Quick Facts

Location: Part of the forebrain, below the corpus callosum
Function: Responsible for relaying information from the sensory receptors to proper areas of the brain where it can be processed
The thalamus in the brain has special centers for glucose and regulates some aspects of  sensory information that is being transmitted to the brain.


What Is More Important in Diabetes?

In Beta Cells of the pancreas where insulin is produced?

Or in cell membranes where it moves receptor proteins?

muscleWhere Insulin Is Produced Or Where It Is Used?

What Is Insulin? Where Does It Come From?

The pancreas is a long, slender organ, most of which is located posterior to the bottom half of the stomach.  Although it is primarily an exocrine gland, secreting a variety of digestive enzymes, the pancreas has an endocrine function. Its pancreatic islets—clusters of cells formerly known as the islets of Langerhans—secrete the hormones glucagon, insulin, somatostatin, and pancreatic polypeptide (PP).


This diagram shows the anatomy of the pancreas. The left, larger side of the pancreas is seated within the curve of the duodenum of the small intestine. The smaller, rightmost tip of the pancreas is located near the spleen. The splenic artery is seen travelling to the spleen, however, it has several branches connecting to the pancreas. An interior view of the pancreas shows that the pancreatic duct is a large tube running through the center of the pancreas. It branches throughout its length in to several horseshoe- shaped pockets of acinar cells. These cells secrete digestive enzymes, which travel down the bile duct and into the small intestine. There are also small pancreatic islets scattered throughout the pancreas. The pancreatic islets secrete the pancreatic hormones insulin and glucagon into the splenic artery. An inset micrograph shows that the pancreatic islets are small discs of tissue consisting of a thin, outer ring called the exocrine acinus, a thicker, inner ring of beta cells and a central circle of alpha cells.

The pancreatic exocrine function involves the acinar cells secreting digestive enzymes that are transported into the small intestine by the pancreatic duct. Its endocrine function involves the secretion of insulin (produced by beta cells) and glucagon 

Two Dimensions of Dr. Ali’s Diabetes Course for Reversing Type 2 Diabetes

          ☞ Insulin Toxicity Course (to Know the Problem Well

         ☞ Diabetes Reversal Course to Know then Solution Well for Reversing Diabetes?


I offer my course in two parts: (1) Dr. Ali’s insulin Toxicity Course; and (2) Dr. Ali’s Diabetes Reversal Course. I attribute the two parts of this course to myself for the simple reason that it makes it easier for people to find it on the internet.

Dr. Ali’s Diabetes Course and Insulin Toxicity Courses are free for everyone, and are posted athttp://www.alidiabetes.org. For my free recipes, please go to http://www.alidiabetes.org. 

Should anyone or any institution wish to teach this course, please send me a note and I will send you written permission to do so without any cost.

Dt. Ali’s Basic, Intermediate, and Advanced Diabetes Courses

 My both Diabetes Course and Insulin Toxicity Course are subdivided into three levels as follows:

  1. Ali’s Basic Diabetes Course
  2. Ali’s Intermediate Diabetes Course
  3. Ali’s Advanced Diabetes Course
  4. Ali’s Basic Insulin Toxicity Course
  5. Ali’s Intermediate Insulin Toxicity Course
  6. Ali’s Advanced Insulin Toxicity Course

What Does the Basic Diabetes Course Cover?

A selected list of questions covered in the Diabetes Course:

  1. What is insulin?
  2. What is insulin toxicity?
  3. How do weight gain and obesity develop?
  4. What is Diabetes?
  5. Can insulin toxicity be reversed?
  6. Can diabetes be reversed?
  7. Is a biology degree necessary for taking Dr. Ali’s Insulin Course and Dr. Ali’s Diabetes Course? The answer: No.


Question: Who Should Consider Basic Insulin and Diabetes Courses?

  1. People interested in health and healing.
  2. Parents interested in the health of their children, especially obesity, diabetes, and healthy living.
  3. Teachers teaching school and college classes.
  4. Healthy study groups in communities, associations, at

 Answer: Teachers teaching school health classes.



Question: Who Should Consider Intermediate Insulin and Diabetes Courses?

Answer: Teachers who teach college-level nutrition and health classes

Anyone whose natural curiosity and interest about the subjects of health, healing, insulin toxicity, weight gain, obesity, and reversal of diabetes has been sharpened by the basic couse.

 Question: Who Should Consider Advanced Insulin and Diabetes Courses?

Doctors and professors who teach advanced health, nutrition, and diabetes classes.

Those and who are iinsulin toxic or has diabetes and who wishes to clear insulin toxicity or has Type 2 diabetes and wishes to reverse the disease.

 Learning and Teaching Materials

  1. Video Seminars: Dr. Ali’s Insulin Toxicity and Diabetes Courses 7 Video seminars (This is Seminar One).
  2. Books: Dr. Ali’s Diabetes Reversal Plan
  3. Courses Taught by Dr. Ali Himself (call 212-873-2444 for course info.


Oxygen Model of Diabetes


My Oxygen Model of Diabetes is an extension of my Oxygen Model of Health and Disease. It is a unifying model that explains all aspects of Type 2 diabetes ( the type that affects more than 95% of individuals afflicted by diabetest—causes, clinical course, consequences, and control—on the basis of disturbed oxygen function. The most important among these compromised and/or blocked functions are: (1) oxygen signaling; (2) oxygen’s ATP energy generation; (3) oxygen’s detergent functions; (4) oxygen’s cellular detox functions; (5) oxygen-regulated cell membrane and matrix functions; (6) oxygen’s cellular repair roles.

The Oxygen Model of Diabetes provides a simple model that allows physicians to reduce complexities of diverse clinical syndromes into a workable simplicity.


This model predicts that ongoing research will reveal that components of acidosis (excess acidity), oxidosis (increased oxidative stress), and CUD (clotting-unclotting dysequilibrium) will be found to play important roles in the pathology and clinical features of Type 2 diabetes.

The crucial importance of  the Unifying Oxygen Model of Type diabetes is that it:

☞ Explains the scientific basis of Type 2 diabetes and its complications;

☞ Sheds light how Type 2 diabetes can be prevented and reversed by addressing all oxygen-related issues;

☞ Elucidates how toxicities of foods, environments, and thoughts cause tissue injury and lead to Type 2 diabetes;

☞ Reveals the mechanisms by which various detox therapies work (Oxygen is the primal detergent which removes cellular grease and allows cells to breathe freely); and

☞ Allows the formulation of rational and effective designs for reversing Type 2 diabetes; and

☞ Provides explanations of mechanisms by which  time-honored natural remedies work to control and prevent Type 2 diabetes.

☞ Provides explanations of mechanisms by which  time-honored natural




Majid Ali, M.D.

Because insulin tests are delayed, often for years. 

In general, fasting Blood sugar test is relied upon for screening for diabetes.  I have seen many cases in which diabetes remained undiagnosed because the fasting blood sugar was below 100 mg/dL. Had a complete three-hour insulin test been done sooner, the diagnosis of diabetes would have been readily made.


Similarly, A1c test is not a reliable test for diagnosis. I have seen this test to also miss diabetes diagnosis. Again,  if three-hour insulin test had been done sooner, the diagnosis of diabetes would have been readily made.


For more info, consider my following free courses on this web site:

  1. Dr. Ali’s Diabetes Course
  2. Dr. Ali’s Insulin Course



Majid Ali, M.D.

Some readers have been dismayed by my statement that diabetes is not a sugar problem.

Below are some questions they have raised. My answers follow the questions.


  1. Ali’s is wrong. Everyone in the world knows that diabetes is a sugar problem,” one dissenter complained.
  2. How can Dr. Ali be wrong and all other doctors in the world be wrong on the sugar-diabetes question?” another asked.
  3. Doesn’t he know that blood sugar is high in diabetes? Why would doctors do blood testing if diabetes was not a sugar problem?
  4. Doctors do blood A1c test. Isn’t it a sugar test,” comes another challenge.


  1. Everyone in the world knows that diabetes is a sugar problem. This not true. Scientists and well-informed doctors know that excess insulin (insulin toxicity) predates diabetes by five, ten, or more years.
  2. All doctors in the world would be wrong on the sugar-diabetes question. No, all doctors would not be wrong. I have never met any doctor who denies the scientific facts that insulin toxicity (hyperinsulinism) predate Type 2 diabetes (the type of diabetes that affects more than 90% of diabetics in the world).
  3. Does Dr. Ali know that blood sugar is high in diabetes? Yes, I know that. But blood sugar begins to rise years after blood insulin levels rise and begin to injure various body organs. I explain my simple point below with a kitchen gas rang” analogy.
  4. Isn’t A1c test a test for blood sugar? Yes, it is, but this test is not a reliable test for screening for diagnosing diabetes. I have seen patients in which A1c is in the normal range and the patients has diabetes, and other patients whose A1c value is higher but a three-hour test for glucose does not sjows evidence of diabetes.


Let us suppose that the gas line in the basement of a house leaks for weeks and then one day there is a fire in the kitchen stove and the house burns down. What would we blame for the house fire, the leaking gas line in the basement or the kitchen stove?


Majid Ali, M.D.

Simple Insulin Truths

Keep insulin low without drugs and live longer,
or keep blood sugar low with drugs and die young.



The global tide of diabetes cannot be understood and stemmed without knowing the fundamentals of the molecular biology of insulin, a subject that is sadly and regularly neglected in the prevailing model of medicine. I wrote Insulin Toxicity Series to shed light on the various faces of this pandemic.

Seven Faces of insulin toxicity:

☞ The first stage of insulin toxicity is without apparent negative health effects recognized by the person.
☞ The second stage of insulin toxicity is with negative health effects recognized by the person but unknown to the doctor.
☞ The third stage of insulin toxicity is tissue injury (in the liver, kidneys, skin, and other organs) unrecognized by a doctor who is clueless about molecular biology of insulin.
☞ The fourth stage of insulin toxicity is prediabetes without tests to detect insulin waste and damages.
☞ The fifth stage of insulin toxicity is Type 2 diabetes with the use of diabetes drugs that add to the insulin activity, hence its toxicity, with the blessings of the American Diabetic Association).
☞ The sixth stage of insulin toxicity is toxicity created by peaks of insulin caused by insulin injections (the end-stage of insulin depletion which is called insulin-dependent diabetes).
☞ The seventh stage of insulin toxicity is loss of vision and blindness (diabetic retinopathy), dialysis (diabetic nephropathy), and increased risk of heart attacks, strokes, autoimmune diseases, inflammatory disorders, and all degenerative states.

I present evidence for all of the above in other articles in my Insulin Toxicity Series:

☞ The Crank and Crank-shaft Model of Insulin Toxicity
☞ The Evidence for the Grease and Detergent Model of Insulin Toxicity
☞ Seven Stages of Insulin Toxicity
☞ Insulin and Metabolic Frugality
☞ Saving the Unborn from Maternal Insulin Toxicity
☞ Insulin-Aging Connections
☞ The Insulin-Sugar Connections
☞ The Insulin-Lipid Connections
☞ The Insulin-Fat Cell Connections (The Intelligent Fat Cells)
☞ The Insulin-Protein Connections
☞ The Insulin-Gut Connections
☞ The Insulin-Liver Connections
☞ The Insulin-Heart Connections
☞ The Insulin-Obesity Connections
☞ The Insulin-Kidney Connections
☞ The Insulin-Brain Connections
☞ The Insulin-Ovary Connections
☞ The Insulin-Eye Connections
☞ Insulin Toxicity and Metformin Mindlessness

The take-home message of this article is: the use of diabetes drugs to lower blood sugar levels without non-drug plans to lower blood insulin levels is feeding the pandemic of insulin toxicity and diabetes. The American Diabetic Association and The New England Journal of Medicine teach doctors to use only drugs to lower blood sugar when what the people really need are programs to de-grease the cell membranes, free up insulin receptor proteins embedded in the membranes, and lower blood insulin levels.

The last article entitled “Insulin Toxicity and Metformin Mindlessness” reveals how many holistic doctors are succumbing to the lure of easy answers with drugs that do not address the real issues.



Dr. Ali’s Insulin Video Library

Google Search for Dr. Ali’s Insulin Library

bout 47,900 results


Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s