Alzheimer’s Disease Is Rooted in Insulin Dysregulation
Majid Ali, M.D.
For detailed information of the subject, please consider my article on this website entitled ” Alzheimer’s Disease Before the Supreme Court of Science – 2017.”
Risk Factors of Alzheimer’s Disease
All risk factors listed below except genetic factors and gender, are risk factors of hyperinsulinism. It is most regrettable that nearly all writers writing about Alzheimer’s disease fail to recognize as a risk factor, let alone one of the most important factor.
1. Advancing Age
2. Genetic Factors ( Apo E4 gene)
3. Female Gender
5. Excessive Alcohol Consumption
10. Elevated Homocysteine Blood Levels
Individuals with a first-degree relative (parent, sibling, or child) diagnosed with Alzheimer’s dementia are more likely to develop the condition. The risk is further increased if more than one family member has the condition. Despite this fact, many individuals with a family history of dementia do not develop the disorder, and many individuals without a family history of dementia go on to develop the disorder.
Genetic testing is available for Alzheimer’s dementia. The gene with the strongest correlation to the development of dementia is apolipoprotein E4, or ApoE4. Individuals who inherit one copy of the ApoE4 gene are at a twofold to fourfold increased risk for developing Alzheimer’s dementia. Individuals who inherit two copies of the gene have a tenfold higher risk, but are not certain to develop dementia. Inheritance of this gene may also be implicated in the onset of dementia at a relatively young age. Routine genetic testing for dementia is not recommended and is usually done as part of research studies.
Dr. Ali’s Alzheimer’s Disease Bibliography
1. Ali M. Oxygen and Aging. (2nd ed.) New York, Canary 21 Press. 2000.
2. Ali M. Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States. Townsend Letter for Doctors and Patients. 2004. 253: 64-65.
3. Ali M. Darwin, Oxygen Homeostasis, and Oxystatic Therapies. Volume X, 3 rd. Edi The Principles and Practice of Integrative Medicine (2009) New York. Institute of Integrative Medicine Press.
4. Ali M. The Principles and Practice of Integrative Medicine Volume XI: 3rd. Edi. Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York. (2009) Institute of Integrative Medicine Press.
5. Ali M. The Principles and Practice of Integrative Medicine Volume XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press.
7. Ali M. Alzheimer’s Disease Before the Supreme Court of Science – 2017. On this Wordpress website.
8. Ali M. Ali M. Altered States of Bowel Ecology. (monograph). Teaneck, NJ, 1980.
9. Ali M. Oxygen, Inflammation, and Castor-Cise Liver Detox. Hormones. Townsend Letter-The examiner of Alternative Medicine. 2007. http://www.townsendletter.com
10. Ali M. Insulin Homeostasis in a General Population ? Shifting the Focus. Townsend Letter for Doctors and Patients. (in press).
11. Ali M. Beyond insulin resistance and syndrome X: The oxidative-dysoxygenative insulin dysfunction (ODID) model. J Capital University of Integrative Medicine. 2001;1:101-141.