Coronary Heart Disease Is Not a Plumbing Problem

Majid Ali, M.D.

New York  212-873-2444

New Jersey . 201-996-0027


 

Endo Health for Vascular Health

Oxygen-Insulin Signaling Matrix

Insulin-Endotoxicity and Cardiovascular Diseases


Two Enemies of the Heart: Conflict and Anger

Conflict cannot be cleared by letting the steam out.

Anger sometimes can be cleared by letting the steam out.


Clearer the Knowledge,

Better the Cardiovascular Health

Two Critical Links: the More the Coronary Plaques, Fewer the Heart Deaths 

The More-Coronary-Plaques-Fewer-Deaths Paradox

Conviction Concerning the Oxygen-Insulin Signaling Matrix


What Is Endothelium?

What Are Good Endo Spices?

What Are Good Endo Herbs


 

What Hurts Endos Most?

Perverted Oxygen-Insulin Signaling Matrix.


 

Crucial Endo Factors

Endothelium Maintains the Vasodilation and Vasoconstriction Balance

inhibition and promotion of the migration and proliferation of smooth muscle cells, fibrinolysis and thrombogenesis as well as prevention and stimulation of the adhesion and aggregation of platelets.


 

What Are Endos?

The vascular endothelium is a multifunctional organ and is critically involved in modulating vascular tone and structure. Endothelial cells produce a wide range of factors that also regulate cellular adhesion, thromboresistance, smooth muscle cell proliferation, and vessel wall inflammation. Thus, endothelial function is important for the homeostasis of the body and its dysfunction is associated with several pathophysiological conditions, including atherosclerosis, hypertension and diabetes. Patients with diabetes invariably show an impairment of endothelium-dependent vasodilation.


Endo Workers

  1.  Reactive Oxygen Species
  2.  Nitric Oxide
  3. Angiotensin II
  4.  EDHF      Endothelium-derived Hyperpolarization Factor
  5. .  Prostacyclin (PGI2
  6.    Antithrombotic (NO and PGI2 both inhibit platelet aggregation) 
  7.   Prothrombotic molecules [von Willebrand factor,
  8.   Plasminogen activator inhibitor-1 (PAI-1)

 

Nitric oxide

NO is a crucial player in vascular homeostasis. NO is synthesized within endothelial cells during conversion of l-arginine to l-citrulline by endothelial nitric oxide synthase (eNOS) [15]. It is released from endothelial cells mainly in response to shear stress elicited by the circulating blood or receptor-operated substances such as acetylcholine, bradykinin, or serotonin [16]. NO diffuses to vascular smooth muscle cells (VSMC) and activates soluble guanylate cyclase (sGC), yielding increased levels of cyclic guanosine-3,5-monophosphate (cGMP) and relaxation of VSMC [1,17]. Additionally, NO also prevents leukocyte adhesion and migration, smooth muscle cell proliferation, platelet adhesion and aggregation, and opposes apoptosis and inflammation having an overall antiatherogenic effect (Fig. 3) [18].


 Therefore, understanding and treating endothelial dysfunction is a major focus in the prevention of vascular complications associated with all forms of diabetes mellitus. The mechanisms of endothelial dysfunction in diabetes may point to new management strategies for the prevention of cardiovascular disease in diabetes. This review will focus on the mechanisms and therapeutics that specifically target endothelial dysfunction in the context of a diabetic setting. Mechanisms including altered glucose metabolism, impaired insulin signaling, low-grade inflammatory state, and increased reactive oxygen species generation will be discussed. The importance of developing new pharmacological approaches that upregulate endothelium-derived nitric oxide synthesis and target key vascular ROS-producing enzymes will be highlighted and new strategies that might prove clinically relevant in preventing the development and/or retarding the progression of diabetes associated vascular complications.


Decreased formation of NO

eNOS is a dimeric enzyme depending on multiple cofactors for its physiological activity and optimal function. eNOS resides in the caveolae and is bound to the caveolar protein, caveolin-1 that inhibits its activity. Elevations in cytoplasmic Ca2 + promote binding of calmodulin to eNOS that subsequently displaces caveolin and activates eNOS


 

Vascular Function and Endothelium

The endothelium is a monolayer of cells covering the vascular lumen. For many years this cell layer was thought to be relatively inert, a mere physical barrier between circulating blood and the underlying tissues. It is now recognized, however, that endothelial cells are metabolically active with important paracrine, endocrine and autocrine functions, indispensable for the maintenance of vascular homeostasis under physiological conditions [1,2]. The multiple functions of vascular endothelium are summarized in Fig. 1 and include regulation of vessel integrity, vascular growth and remodeling, tissue growth and metabolism, immune responses, cell adhesion, angiogenesis, hemostasis and vascular permeability. The endothelium plays a pivotal role in the regulation of vascular tone, controlling tissue blood flow and inflammatory responses and maintaining blood fluidity.


 

Crucial Endo Factors

Endothelium Maintains the Vasodilation and Vasoconstriction Balance

, inhibition and promotion of the migration and proliferation of smooth muscle cells, fibrinolysis and thrombogenesis as well as prevention and stimulation of the adhesion and aggregation of platelets.


  1.  Reactive Oxygen Species
  2. Nitric Oxide
  3. Angiotensin II
  4.  EDHF      Endothelium-derived Hyperpolarization Factor
  5. .  Prostacyclin (PGI2
  6.    Antithrombotic (NO and PGI2 both inhibit platelet aggregation) 
  7.   Prothrombotic molecules [von Willebrand factor,
  8.   Plasminogen activator inhibitor-1 (PAI-1)

Endothelium-derived factors with vasodilatory and antiproliferative effects include endothelium-derived hyperpolarization factor (EDHF) [], nitric oxide (NO) [8,9] and prostacyclin (PGI2) [10], while endothelin-1 (ET-1) [11], angiotensin II and reactive oxygen species (ROS) are among the mediators that exert vasoconstrictor effects [12,13]. Endothelial cells also produce antithrombotic (NO and PGI2 both inhibit platelet aggregation) and prothrombotic molecules [von Willebrand factor, which promotes platelet aggregation, and plasminogen activator inhibitor-1 (PAI-1), which inhibits fibrinolysis] [5].

As a major regulator of vascular homeostasis, the endothelium maintains the balance between vasodilation and vasoconstriction, inhibition and promotion of the migration and proliferation of smooth muscle cells, fibrinolysis and thrombogenesis as well as prevention and stimulation of the adhesion and aggregation of platelets (Fig. 2) [5]. Disturbing this tightly regulated equilibrium leads to endothelial dysfunction.


 

Many Faces of Endothelium

Fig. 1. Multiple functions of endothelium.


 

Spices and Herbs For Endo Health

 

 

 

 

 

 

 

 

Fatty Liver Or Fatty Liver Disease or Insulin-Toxic Liver

 

Majid Ali, M.D.

Insulin -Toxic Liver Disease – A Global Pandemic


.

A free course on Liver Health NOW | Majid Ali MD | The Ali Academy …

Nov 28, 2014 – Liver HEALTH NOW It is one of the profound ironies of prevailing drug medicine that there is no concept of liver detox among liver specialists. Treatment of most liver diseases in the hands of gastroenterologists and hepatologists is confined to the use of immune-suppressive therapies, such as steroids, …

A course on Liver Detox with Natural Therapies | The Ali … – Majid Ali MD

Dec 18, 2014 – This is an Update March 17, 2015 Dietary sugar consumption, in particular sugar-sweetened beverages and the monosaccharide fructose, has been linked to the incidence and severity of non-alcoholic fatty liver disease (NAFLD). Intervention studies in both animals and humans have shown large doses of …

Liver Disorders | The Ali Academy Community – Majid Ali MD

Mar 30, 2015 – Liver HEALTH NOW It is one of the profound ironies of prevailing drug medicine that there is no concept of liver detox among liver specialists. Treatment of most liver diseases in the hands of gastroenterologists and hepatologists is confined to the use of immune-suppressive therapies, such as steroids, …

Liver videos part 3 | The Ali Academy Community – Majid Ali MD

Liver Detox for Fibromyalgia from Majid Ali on Vimeo. Liver Hemagioma and Vascular Malformation of the Brain from Majid Ali on Vimeo. Hemagioma of the Liver – Insignificant Malformation from Majid Alion Vimeo. PLEASE HELP OUR STAFF! The goal of this website is to provide thousands of free videos and articles …

Dr. Ali’s Bowel Detox and Colon Cleanse | The Ali Academy Community

Nov 17, 2012 – Majid Ali, M.D.. Here are the crucial lessons which my patients, my microscopes, and my friends on my autopsy tables taught me in the last fifty-four years: * As roots are to roses, so the bowels to the brain. * As roots are to roses, so the bowels to the heart. * As roots are to roses, so the bowels to the liver.

Liver Detox – Majid Ali MD

Dec 2, 2017 – Majid Ali, M.D. This Article Is a Part of Dr. A. Liver Course Series The Liver Is the MainDetoxification Organ of the Body. Dr. Ali’s Top Seven Suggestions for liver detox are: 1. Love Without Notions of control 2. Restoring oxygen signaling 3. Prayer 4. Insulin Optimization 5. Dr. Ali’s Breakfast (with lecithin and …

Dr. Ali’s Liver Detox Course – Majid Ali MD

Dec 2, 2017 – Majid Ali, M.D. This Article Is a Part of Dr. A. Liver Course Series The Liver Is the MainDetoxification Organ of the Body. Dr. Ali’s Top Seven Suggestions for liver detox are: 1. Love Without Notions of control 2. Restoring oxygen signaling 3. Prayer 4. Insulin Optimization 5. Dr. Ali’s Breakfast (with lecithin and …

Liver Detox for Fibromyalgia -Majid Ali, MD on Vimeo

https://vimeo.com › Majid Ali › Videos
Apr 16, 2014 – Uploaded by Majid Ali

Professor Majid Ali shares information about “Liver Detox for Fibromyalgia”

Dr. Ali’s Liver Detox – Dr. Ali’s Virtual Medical Library

drali1.org/dr__ali’s_liver_detox.htm

Dr. Ali’s Liver Detox. Majid Ali, M.D.. In this DVD video seminar, Prof. Ali describes his guidelines for gentle daily liver detox. He explains the advantages of this approach over intense one-week to 3-week programs which, notwithstanding their temporary benefits, often create adverse effects. LIST OF VIDEOS. * Master DVD …

Insulin Toxicity – Early Signs

Majid Ali, M.D.

Early Signs of Insulin Toxicity Are Diabetes Complications Not Diagnosed for Years Before They Actually Diagnosed.  


 

What Google Told Me About Complications of Diabetes

  
·       Cardiovascular disease. …
·       Nerve damage (neuropathy). …
·       Kidney damage (nephropathy). …
·       Eye damage (retinopathy). …
·       Foot damage. …
·       Skin conditions. …
·       Hearing impairment. …
·       Alzheimer’s disease

What My PatientsTaught me About Insulin Toxicity

Blood insulin test should be done for the following conditions since there is high probability that the underlying fires of these conditions are fed by insulin toxicity.
 
·       Loss of Vigor
·       Weight gain
·       Course skin
·       Acne in teenager
        Skin pigmentation changes
·       Facial hour for young women
·       Tingling and numbness in toes and fingers
·       Brain fog
·       Cognitive difficulties
·       Memory loss
·       Any infections that do not heal
·       Any inflammation that does not heal
·       Colitis of immune-inflammatory disorders
·       Arthritis of immune-inflammatory disorders
·       Connective tissue diseases
·       Any skin conditions that do not heal
·       Neurodermatitis
·       Brain atrophy
·       Brain degenerative conditions
·       Rising blood creatinine level
·       Rising liver enzyme levels
·       Rising CRP test results
·       Liver ultrasound with fatty liver disease, steatosis, or steatonecrosis.


 

DR. Ali’s Library of Diabetes

 

 


Top Seven for Diabetes Foot

Majid Ali, M.D.


What Is Diabetic Foot?

What Is Insulin Foot?

A diabetic foot is a generic term used for any chronic pathologic lesions (conditions) that results directly from diabetes (Type I, Type II, or other types or diabetes, or from chronic complications of diabetes of any type.
Since hyperinsulinism (insulin toxicity) predates Type 2 diabetes (T2D, the common form of diabetes mellitus)) by five, ten, or more years, and since diabetes foot often develops during these years, the term “insulin foot” is more appropriate than diabetes foot. The use of insulin foot draws sharp focus on insulin, both for the patient and the physician.

Signs and Symptoms of Insulin Foot

1. Pain
2. Low skin temperature with or without cold sensitivity
3. Numbness, tingling, pins and needles
4. Skin color change (redness, pigmentation change)
5. Loss of sensation (leading to cigarette burn for instance)
6. Slow healing wounds
7. Slow healing infections

Common terms used  for diabetic foot include:
 
1.   Diabetic nerve pain
2.   Diabetic neuropathy
3.   Diabetic foot pain
4.   Diabetic peripheral nerve dysfunction
5.   Diabetic peripheral vascular dysfunction

Top Seven for Diabetic Foot 

1.     Optimal Diabetes Control With Insulin Detox
2.     Attention to Early Negative Changes
            2. a  Poor circulation
            2.b  Pigmentation changes
            2.c   Nail fungus
            2.d  Poorly healing small wounds
            2.e  Poorly healing minor infections
            2.f  Foot and ankle puffiness
            2.g  Local pressure changes
3.        Vigorous treatment of early infections         
4.       Castor oil topical for early inflammatory lesions
5.       Hydrogen Peroxide foot soaks
6.       Nutrient Supplementation for Improved Circulation


 


Dr. Ali’s VideoLibrary

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This is a pragmatic view of an integrative physician, not a delusional plausibility of an ideologue. I hope you will consider the Program. It should serve you well for life. Kindest regards, Majid Ali, M.D.. Majid Ali, M.D. Updated June 20, 2010. COURSE 1: PHILOSOPHY OF BEING ONE’S OWN PRIMARY PHYSICIAN.

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Buy and Download > Description. In this 35-minute video seminar, Professor Majid AliM.D. explains why he rejects the diagnostic criteria for prediabetes established by the American Diabetes Association (ADA) and the World Health Organization (WHO). He asserts diabetes can neither be prevented nor reversed as long …

Dr. Ali’s VideoLibrary
drali1.org/healer_course.htm
This is a pragmatic view of an integrative physician, not a delusional plausibility of an ideologue. I hope you will consider the Program. It should serve you well for life. Kindest regards, Majid Ali, M.D.. Majid Ali, M.D. Updated June 20, 2010. COURSE 1: PHILOSOPHY OF BEING ONE’S OWN PRIMARY PHYSICIAN.
Jun 11, 2014 – The matters of doubt and uncertainty are of central importance to Being One’s Own Primary Physician. The uncertainty principle offers us an antidote to the risk of habitual thinking, blind trust, and static belief that impedes learning and threatens success. The subject of uncertainty brings to mind some of the …
May 11, 2014 – If your symptoms recurred after sinus surgery, please think of mold allergy, mold infections, and mold toxins. For the … Being One’s Own Personal Physician. I define … For example, a forty-year-old man who develops acute sinusitis and fever cannot be his primary physician for that acute illness. However …
Aug 20, 2014 – Majid Ali, M.D.. My patients with coronary heart disease have taught me this: Heart disease is a state of separation from one’s nature. This separation is caused by: 1. Deep disappointments of ….. For reversing coronary artery disease one must become one’s own primary physician. This, however, takes time.
Dec 25, 2014 – In the United States today, blocker drugs, stents, and bypass procedures are promoted as the primarytherapies for coronary artery disease. … This is what I call being one’s own doctor—cardiologist in the current context. … A Chick Comes Out of an Egg and Drops Dead of a Heart AttackMajid Ali MD …
Jul 8, 2014 – What Is Allergy? A Great Masquerader That Must Be Banished to Enjoy Health Majid Ali, M.D. Allergy is a great masquerader of the immune system. Sneezing, stuffy nose, itchy eyes, skin rashes, and sinusitis are only the surface problems in allergy. There are many deeper and more serious problems …
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Get appointment information and hours of operation for Majid Ali, practicing Public Health & General Preventive Medicine doctor in New York, NY.
Missing: being ‎own
Being One’s Own Primary PhysicianMajid Ali, M.D.. I define disease in two ways: * First, disease is a state of separation from one’s nature. * Second, disease is a state of evolution in reverse. Since no one else can know one’s nature —nor the degrees of separation from it—one can have only one authenticphysician: …
Sep 3, 2014 – Posts about Majid Ali MD written by Majid Ali MD. … far beyond the classical and wholly inadequate notion of it being a process characterized by edema, erythema, tenderness, pain, and infiltrate of inflammatory cells. ….. For reversing coronary artery disease one must become one’s own primary physician.

store.payloadz.com › Movies and Videos › Educational
Buy and Download > Description. In this 35-minute video seminar, Professor Majid AliM.D. explains why he rejects the diagnostic criteria for prediabetes established by the American Diabetes Association (ADA) and the World Health Organization (WHO). He asserts diabetes can neither be prevented nor reversed as long …

Jun 11, 2014 – The matters of doubt and uncertainty are of central importance to Being One’s Own Primary Physician. The uncertainty principle offers us an antidote to the risk of habitual thinking, blind trust, and static belief that impedes learning and threatens success. The subject of uncertainty brings to mind some of the …
May 11, 2014 – If your symptoms recurred after sinus surgery, please think of mold allergy, mold infections, and mold toxins. For the … Being One’s Own Personal Physician. I define … For example, a forty-year-old man who develops acute sinusitis and fever cannot be his primary physician for that acute illness. However …
Aug 20, 2014 – Majid Ali, M.D.. My patients with coronary heart disease have taught me this: Heart disease is a state of separation from one’s nature. This separation is caused by: 1. Deep disappointments of ….. For reversing coronary artery disease one must become one’s own primary physician. This, however, takes time.
Dec 25, 2014 – In the United States today, blocker drugs, stents, and bypass procedures are promoted as the primarytherapies for coronary artery disease. … This is what I call being one’s own doctor—cardiologist in the current context. … A Chick Comes Out of an Egg and Drops Dead of a Heart AttackMajid Ali MD …
Jul 8, 2014 – What Is Allergy? A Great Masquerader That Must Be Banished to Enjoy Health Majid Ali, M.D. Allergy is a great masquerader of the immune system. Sneezing, stuffy nose, itchy eyes, skin rashes, and sinusitis are only the surface problems in allergy. There are many deeper and more serious problems …
Rating: 5 – ‎5 reviews
Get appointment information and hours of operation for Majid Ali, practicing Public Health & General Preventive Medicine doctor in New York, NY.
Missing: being ‎own
Being One’s Own Primary PhysicianMajid Ali, M.D.. I define disease in two ways: * First, disease is a state of separation from one’s nature. * Second, disease is a state of evolution in reverse. Since no one else can know one’s nature —nor the degrees of separation from it—one can have only one authenticphysician: …
Sep 3, 2014 – Posts about Majid Ali MD written by Majid Ali MD. … far beyond the classical and wholly inadequate notion of it being a process characterized by edema, erythema, tenderness, pain, and infiltrate of inflammatory cells. ….. For reversing coronary artery disease one must become one’s own primary physician.

store.payloadz.com › Movies and Videos › Educational
Buy and Download > Description. In this 35-minute video seminar, Professor Majid AliM.D. explains why he rejects the diagnostic criteria for prediabetes established by the American Diabetes Association (ADA) and the World Health Organization (WHO). He asserts diabetes can neither be prevented nor reversed as long …

 


Top Seven for Diabetic Foot

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Majid Ali (majidalimd@aol.com)To:you Details

The Dysoxic-Insulin-Toxic Liver State

Majid Ali, M.D.

A  Crucially Needed Perspective of Pandemic

A Time to Replace Obsolete Diagnostic Labels


 

Fatty Liver

Non-Alcoholic Fatty Liver Disease (NAFLD)

Non-Alcoholic Steatohepatitis (NASH)

The Dysoxic-Insulin-Toxic Liver State

 


Restoring Gut Microbiota for Restoring Liver Health


Oxidation-reduction (Redox) Dynamics

In the late 1970s, I began a study of the impact of redox (oxidation-reduction) dynamics on human health and disease, as well as the aging processes. In 1983, I offered my initial observations and reflections on the subject in a monograph entitled Spontaneity of Oxidation in Nature and Aging.1 This was followed by work  in redox dynamics of cell membrane, matrix, and mitochondria, as well as in the use of nutrients for preserving and/or restoring redox dynamics in cellular systems.2-16 In 2004, I began publication of a monthly column on oxygen homeostasis in  Townsend Letter-The examiner of Alternative Medicine. My initial columns was entitled  Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States.17 In a series of follow-up articles of molecular biology of oxygen and oxygen signaling, I described scientific basis and rationale of oxygen models of chronic diseases as well as environmentally triggered and perpetuated chinical syndrome.16-24  My interest and work in molecular biology of insulin, insulin signaling, insulin as the primal energy and life span hormone.25-35   was rooted in the earlier work in molecular biology of oxygen. My concurrent work in gut immunopathology and surgical pathology clarified the integration of the gut, liver, and bowel ecosystem. From these works accrued a clear recognition that the subjects of nutrition, environmental exposures, and imme-inflammatory responses are far too intricately intertwined to allow deliberations of these subjects as discrete clinical disorders.
 

 


The Dysoxic-Insulin-toxic Liver State

 
In 1968, I began my pathology residency and my microscope opened new vistas for me in the world of the liver. Accumulation of fat droplets in the liver cells was always attributed to alcohol intake and the change was harmless except when it caused liver cell death and scarring, leading in some instances to dreaded liver disease called cirrhosis. Within ten years, I recognized the folly of this prevailing and benign view. Fat build-up in the liver cells, I recognized was, the beginning of liver cell death.  In Oxygen and Aging (2000), I devoted large sections of the book to liver diseases and the centrality of the organ in all detoxification pathways of the body.  I recognized a workable simplicity to cope with maddening complexities of the brain, blood, liver, and the gut: The  liver, it seemed to me, was  the guardian angel of the brain and the bowel of the liver.
 
Work with the molecular biology of oxygen revealed a much deeper dimension of the liver: fatty change of the liver was nearly always associated with hyperinsulinism (insulin toxicity). This was the beginning of the conception of the “dysoxic insulin-toxic liver state to replace terms like steatosis of the liver (fatty liver), NAFLD (non-alcholoc fatty liver disease), and steatohepatitis.
 
The term dysoxic insulin-toxic liver not only provides deeper insights into the nature of the diseases abut also clear guidelines for the prevention and reversal of the liver disease triggered and perpetuated by dietary, environmental, metabolic, and insulin-related factors.

 


The Dysoxic-Insulin-toxic Liver State Is Reversible

References

1.     Ali M. . Spontaneity of Oxidation in Nature Nature and Aging,  (monograph). Teaneck, NJ, 1983.
2.     Ali M. Ali M. The agony and death of a cell. In: Syllabus of the Instruction Course of the American Academy of Environmental Medicine. Denver, Colorado, 1985.
3.     Ali M. Ali M.  Oxidative Cell Membrane Disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
4.     Ali M. Nutrition, oxidant stress, and the immune system: Free radical pathology.  Syllabus. American Academy of Environmental Medicine. 1988. 13th Instructional Course. Part I. Denver, Colrado. pp147-168. Clinical Ecology Publications. Denver, Colorado. 
5.     Ali M:  Ascorbic acid reverses abnormal erythrocyte morphology in chronic fatigue syndrome (abstract). Am J Clin Pathol , 94:515,1990.
6.     Ali M. The Agony and Death of a Cell. Curriculum 15th. Instructional Course. The American Academy of Environmental Medicine. 1990. Denver, Colorado. Clinical Ecology Publications, Inc.
7.     Ali M. Molecular basis for the use of antioxidants to regulate plasma membrane dynamics in allergic disorders.  abstracts, Annual Meeting of the American Academy of Otolaryngic Allergy, page 30, 199l.
8.     Ascorbic acid prevents platelet aggregation by norepinephrine, collagen, ADP and ristocetin (abstract), Am J Clin Pathol, 95:281, 1991.
9.     Ali M:  Molecular basis for the use of antioxidants to regulate plasma membrane dynamics in allergic disorders.  abstracts, Annual Meeting of the American Academy of Otolaryngic Allergy, page 30, 199l.
10. Ali M.  Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States. Townsend Letter for Doctors and Patients. 2004. 253: 64-65 (2004).
11.  
12. . Ali M: The Canary and Chronic Fatigue (1st ed). Denville, New Jersey, Life Span Books 1994.
13. Ali M. Ali O: AA oxidopathy: the core pathogenic mechanism of ischemic heart disease. J Integrative   Medicine 1997;1:6-112.
14. Ali M: Oxidative regression to primordial cellular ecology. J Integrative Medicine 1998; 2:4-55.
15.  Ali M. Ali M: Oxidative menopausal dysfunction (OMD-II):hormone replacement therapy (HRT) or receptor   restoration therapy (RRT)? J Integrative Medicine 1998;2:125-139.
16. Ali M. Oxygen and Aging. (Ist ed.) New York, Canary 21 Press. Aging Healthfully Book 2000.
17. Ali M. Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States. Townsend Letter for Doctors and Patients. 2004. 253: 64-65 (2004).
18. Ali M. Oxygen governs the inflammatory response and adjudicates the man-microbe conflicts. Townsend Letter for Doctors and Patients. 2005;262:98-103.
19. Ali M. Oxygen, Inflammation, and Castor-Cise Liver Detox. Hormones. Townsend Letter-The examiner of Alternative Medicine. 2007. Published online. http://www.townsendletter.com/Dec2007/oxygen1207.htm
20. Ali M. Ali M. Petrochemical Illness and philic-phobic dysequilibrium in the Gulf of Mexico. Townsend Letter-The examiner of Alternative Medicine. 2010;76:79. November 2010.
21. Ali M. The Dysox Model of Obesity.  J Integrative Medicine. 2005;10:11-17.
22. Ali M. Dysoxic-Insulotoxic  Liver Disease. Feb. 19, 2018.
23. Drew L  Drug development [Hepatic} Sprint finish. Nature. 2017;551:S87.
24. Eisenstein Michael. Diagnostics. Missing the Point print. Nature. 2017;551:S90-93.
25.  Scott Andrew. Menace in the Microbiota. Nature. 2017;551:S94-5.
26.  Nogrady B. A Growing concern. Nature. 2017;551:S96.
27. Ali. M. Oxygen governs the inflammatory response and adjudicates the man-microbe conflicts. Townsend Letter for Doctors and Patients. 2005;262:98-103.
28. Ali M. Oxygen, Insulin Toxicity, Inflammation, And  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.
29. Ali M. Petrochemical Illness and philic-phobic dysequilibrium in the Gulf of Mexico. Townsend Letter-The examiner of Alternative Medicine. 2010;76:79. November 2010.
30. Ali M. The Dysox Model of Obesity.  J Integrative Medicine. 2005;10:11-17.
31. Ali Recent advances in integrative allergy care. Current Opinion in Otolaryngology & Head and Neck Surgery 2000;8:260-266.
32. Ali M. Oxidative coagulopathy in environmental illness. Environmental Management and Health. 2000;11:175-191.
33. Ali M: Oxidative regression to primordial cellular ecology. J Integrative Medicine 1998; 2:4-55.
34. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.
35.  Ali M. Ali M. Hydrogen peroxide therapies: Recent Insights into oxystatic and antimicrobial actions. Townsend Letter for Doctors and Patients. 2004, 255;140-143.

Dr. Ali’s Diabetes Diet Plan

 

Dr. Nutrients, Herbs, and Spices As Cellular Detergents

Majid Ali, M.D.


Two Golden Rules:
1. Start Low, Build Slow Rule
2. The Rotation Rule

As for the first rule, it is always prudent to test one’s own metabolic uniqueness by starting with a small dose, such as one-half of the dose in the guidelines and then gradually increase it to the full suggested dose when full clinical tolerance of the remedy has been assured.

The rotation in the second rule can be alternate days, two-days-on-one-day-off, or weekly.

 


Purpose of Supplements
To restore insulin function and regulate
blood glucose level by correcting insulin dyregulation.
restoring , the insulin receptor
protein in cell membranes needs to de-
greased with cellular detergents. 

 

To reverse pre-diabetes and diabetes (completely or partially), my primary objective is to lower both blood sugar and insulin levels by making insulin work better. For individuals with pre-diabetes with insulin toxicity but without high blood sugar levels, my goal is to lower blood insulin levels by increasing insulin efficiency.


Dr. Ali’s Diabetes Diet Plan

My Diabetes Reversal Plan has two components:

1. A plan of food choices to prevent sugar spikes that trigger insulin spikes, and

2. A plan to do daily gentle bowel and liver detox.

In the Table 2 below, I present a case study to show how blood glucose and insulin levels were lowered (by increasing insulin efficiency) with the clinical application of Dr. Ali’s Insulin Reduction Protocol. I follow this with some explanatory comments. In Table 1, I present the insulin and glucose values of an individual in good metabolic health.


Link to Dr. Ali’s Diabetes Diet Plan

https://alidiabetes.org/2018/02/05/dr-alis-diabetes-diet-plan/


 

 

Table 1. Insulin-conserving Profile of a 77-Yr-Old Metabolically Fit 5′ 5″ Man Weighing 133 Lbs. He Was Seen for Allergy Treatment.

6.23. 2010

Fasting

1 Hr

2 Hr

3 Hr

Insulin

<2

24

29

30

Glucose

78

96

75

71

Table 2. Concurrent Reduction of Blood Insulin and Blood Sugar Levels With Dr. Ali’s Insulin Reduction Protocol in a 58-Yr-Old Woman With Complete Loss of Hair (Alopecia), Chronic Fatigue, Memory Deficit, Underactive Thyroid Gland, Allergy, and Mood Swings.

10.28.10

Fasting

1 Hr

2 Hr

3 Hr

Insulin

9.7

184.4

35.3

24

Glucose

102

133

79

73

11.23.1202

Insulin

12.7

87.7

50.2

 

Glucose

96

117

77

 

Diabetes Reversal Requires a Philosophy of Healing

Diabetes Type 2 can be reversed neither with the denial of dieting nor with euphoria of eating. Diabetes can be reversed only with a philosophy of eating and living. It requires knowing the difference between being “diabetes-literate” and “healing-literate.” Diabetes is the number one cause of blindness, neuropathy, toe and limb amputations, kidney failure leading to dialysis, and increased risk of strokes, memory loss, and heart attacks. So reversing diabetes is an act of self-compassion. If these words pull you toward making an honest attempt to lose diabetes Type 2, please consider studying “Dr. Ali’s Course on Healing” (available at www.aliacademy.com).


Five Important Facts About Insulin-Wise and Insulin-Unwise Foods

I coined the terms Insulin-Wise and Insulin-Unwise Foods to raise consciousness about the serious adverse effects of insulin spikes on all cell populations in the body.

1. Insulin in excess (insulin toxicity) is fattening and inflaming.

2. Healthy fats are insulin-friendly.

3. Healthy proteins are insulin-friendly.

4. All breads, pastas, fruits and fruit juices, and sugars are insulin-unfriendly.

5. Vegetables are insulin-friendly.


Below are guidelines for Dr. Ali’s Insulin Diet. If initially this diet plan is found to be too hard and restrictive, one or two days a week may be taken as free days. Of course, some insulin benefits will be lost on such days.

Insulin-Friendly Breakfast for Saving Insulin and Preventing Diabetes

1. Please consider “Dr. Ali’s Breakfast” (protein shake described below) four or five days a week.

2.` Take eggs and vegetables for breakfast the remaining two days.

3. No fruit juices, breads, or toast.

Insulin-Friendly Lunch for Saving Insulin and Preventing Diabetes

1. Large salad with goat cheese, chicken, or fish. All the olive or sesame oil you wish.

2. Uncooked, steamed, or lightly stir-fried vegetables. All the olive or sesame oil you wish.

Mid-Afternoon Snack

Use four to six ounces of the Dr. Ali’s Breakfast shake (prepared in the morning and carried to work).

Insulin-Friendly Dinner for Saving Insulin and Preventing Diabetes

 

1. All healthy fats and oils

2. All healthy proteins

3. Uncooked, steamed, or lightly stir-fried vegetables with melted butter or olive oil (to your heart’s content).

Optimal Breakfast Choices for Diabetes

Dr. Ali’s Breakfast on five to six days per week comprising: (1) two tablespoons of a protein powder containing 85 to 90 percent calories in proteins and peptides; (2) two tablespoons of a granular lecithin; (3) two tablespoons of freshly ground flaxseed (the use of a coffee grinder is recommended); (4) 12 to 16 ounces of organic vegetable juice (avoiding or minimizing the use of carrots and red beets); and (5) 12 to 16 ounces of water. A few ounces of seltzer water or a few drops of lemon juice may be added to suit personal taste. I personally consume this mixture in portions of six to eight ounces with my morning nutrient and herbal protocols during the period of my morning exercise, meditation, and preparation for work. I have not yet encountered any negative impact of the protein content in this breakfast on renal function. Still, individuals with serum creatinine levels above the normal range need to be monitored for renal function.

Insulin Channel on YouTube Science, Health, and Healing Encyclopedia

I offer about 75 videos on insulin in health and disease on my my YouTube Science, Health, and Healing Encyclopedia. I especially recommend the channel entitled “Seven Faces of Insulin Toxicity”:http://www.youtube.com/watch?v=zxtVhe0mnf4

Insulin – the Minister of Energy and Metabolism

I designate insulin to be the Minister of Energy and Metabolism to the Oxygen king of the human body. By its signals, it regulates the energy of all cells in the body. Of necessity, this means that insulin has a role to play in the health preservation of all such cells.

Insulin is a hormone produced in specialized cells of the pancreas gland called beta cells. It is a string made up of 51 amino acid molecules and has a molecular weight of 5808 Daltons. Insulin performs diverse metabolic and non-metabolic functions in the body. As for metabolism, its major functions include the transfer of glucose from the blood into the liver and muscle cells for storage and into the fatty tissues to stop the use of fat as fuel. Among the major non-metabolic functions are its roles in cellular development, differentiation, and death.

Related Articles

 Oxygen Homeostasis and Oxygen Models of Diseases

* Insulin Homeostasis and Diabetes

* Insulin-Wise Foods, Insulin-Saving Recipes

* Dr. Ali’s Insulin Reduction Protocol – For Improving Insulin Efficiency

* Dr. Ali’s Insulin-Wise Breakfast

* Dr. Ali’s Insulin-Wise Breakfast – Personalized

* Insulin-saving Tuna-Tiki

* Insulin-saving Vege-Tiki

* Insulin-saving Palak-Tiki

* Insulin-saving Almond snack

 

 

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